Why is propofol rarely used in small mammals for anesthesia?

Propofol is primarily administered intravenously, which allows for rapid onset of anesthesia but also presents certain risks in small mammals, including the potential to cause apnea. Apnea, or the temporary cessation of breath, can be particularly concerning in small mammals due to their size and physiology. This makes it challenging to monitor and manage their respiratory function effectively during anesthesia, leading to an increased risk of complications. While other factors, such as cost and effectiveness for short procedures, may play a role in anesthesia choice, the safety concerns related to intravenous administration and the risk of apnea are the primary reasons propofol is rarely used in small mammal anesthesia. This highlights the importance of understanding not just the administration route and properties of the anesthetic, but also the specific species physiology and their tolerance to various anesthetic agents.